CX3CR1 and nasopharyngeal carcinoma: Moreover, microglia have been shown to mediate exercise-induced increases in NPC proliferation via signalling through the microglial receptor C-X3-C motif chemokine receptor 1 (CX3CR1) and the neural cell-released chemokine CX3CL154, further suggesting that chemokine signalling is an important mediator within the neurogenic niche.