Similar elevations in Pfkfb3 mRNA (Fig. 3f) and protein (Fig. 3g) expression were observed in a variety of established human breast cancer cell lines relative to HMECs; however, it should be noted that the correlation between Pfkfb3 mRNA and protein expression varies slightly within human breast cancer cell lines. The gene discussed is PFKFB3; the disease is breast carcinoma.