To further characterize this regulon, we examined the functional enrichment of the 198 genes in the intersection (Supplementary Table 2, Supplementary Data 5d), and found that they are enriched for Gene Ontology (GO) terms related to immune response (in particular, the Fc-gamma receptor pathway), cytoskeletal organization, and focal adhesion, and for genes that interact with WAS. WAS, which encodes Wiscott-Aldrich Syndrome Protein, transduces signals from the cell surface to the actin cytoskeleton in response to infection, and is required for a variety of immunological cell functions. This evidence concerns the gene WAS and infection.