MAPK7 and osteoporosis: The morphology of the osteoporosis rats’ femur was analyzed using HE staining, the results of which revealed that, compared with the sham group, the trabecular bone of the OVX, OVX + NC, OVX + ERK-5 shRNA, OVX + ERK-5 overexpression groups was obviously slender, the coloration was faint, the margin was rough, the structure integrity was poor, the fragment appeared, the number of the trabecular was significantly reduced, and the interval obviously increased (P<0.05).