There were no differences among the treatment groups for Ki67 or cleaved caspase-3 staining, except for a significant increase in caspase staining (p = 0.024) in the unirradiated flank tumor when analyzing anti-PD-L1 combined with XRT compared to anti-PD-L1 monotherapy (Fig. 2c and d). This evidence concerns the gene CASP3 and neoplasm.