Consistent with our findings, Nagasawa et al. [30] suggested that high levels of plasma total adiponectin can be a predictor of stroke mortality during the 17 months following an episode of acute stroke in patients, while another study confirmed that plasma total adiponectin values may help to classify stroke subtypes and predict neurological severity and functional outcome in ischemic stroke patients [31]. This evidence concerns the gene ADIPOQ and ischemic stroke.