DS-8895a is a humanized anti-EPHA2 IgG1 monoclonal antibody (Additional file 1) that is afucosylated to enhance ADCC (POTELLIGENT®; BioWa Inc., Princeton, NJ, USA) and is expected to produce antitumor effects on EPHA2-overexpressing tumor cells through ADCC, as demonstrated in pre-clinical studies [23]. Here, EPHA2 is linked to neoplasm.