He was diagnosed as SLE in local hospital for facial maculopapulae, arthritis, pericardial effusion, hemolytic anemia and severe thrombocytopenia, accompanying with high titers of antinuclear antibody (ANA), anticardiolipin antibody (ACL), as well as decreased complements, according to the Systemic Lupus International Collaborating Clinics (SLICC) criteria [5]. This evidence concerns the gene BTG3 and pericardial effusion.