CCND1 and head and neck squamous cell carcinoma: Similarly, other reported downstream target genes like CDK4, CCND1, CDH1 and BCL2 did not respond to up- or downregulation of CASC9 in HNSCC cells and only BCL2 and E-Cadherin (CDH1) expression correlated moderately with CASC9 expression across our cell line panel, indicating that they may be rather coregulated by common underlying mechanisms.