The results of KEGG signaling pathway analysis showed that the DEG was markedly enriched in extracellular matrix (ECM)-receptor interaction, proteoglycans in cancer, focal adhesion, mucin type o-glycan biosynthesis and phosphoinositide 3-kinase- protein kinase B (PI3K- Akt) signaling pathway (Table 1). The gene discussed is AKT1; the disease is cancer.