EP300 and chronic obstructive pulmonary disease: All the three took into account different miRNAs and corresponding antagomiRs, but the results were seen to be overall positive, except the above reported work by Hsu et al. [76], which highlighted the pivotal importance of combining antagomiRs with protein kinase R to increase antiviral stress granules formation, induction of p300 and IFN-β in COPD primary bronchial epithelial cells.