ALK and non-small cell lung carcinoma: Camidge et al. [16] has shown that analysis of ≥60 cells from ≥4 selected tumor areas of a NSCLC specimen can reach 100% specificity and 100% of sensitivity for ALK rearrangement testing, although the Vysis ALK Break Apart FISH probe set used in their study is slightly different for coverages of both 5′ALK and 3′ALK probe from the one approved by the FDA.