MDSCs are attracted to tumor sites in response to various cytokines (CCL2, CCL5, and CSF1 for M-MDSCs, and CXCL1, CXCL5, CXCL6, CXCL8, and CXCL12 for PMN-MDSCs) [176]. Here, CXCL8 is linked to neoplasm.