Several studies have demonstrated the association between MMD and allelic and haplotypic differences of HLA, including both HLA class I and class II alleles (e.g., HLA-A*24, HLA-B*54, HLA-DRB1*04:05, and HLA-DQB1*04:01) in multiple cohorts of East Asians [18–21], as well as in Europeans [22]. This evidence concerns the gene HLA-DQB1 and multiminicore myopathy.