HLA-DRB1 and hemorrhagic stroke: In addition, the HLA-DRB1*04:10-positive group had more females (frequency 92.3% vs. 75.6%; P = 0.297), younger patients (mean age of onset 30.1 ± 13.3 vs. 35.4 ± 16.0 years in the control group; P = 0.206), and higher incidences of hemorrhagic stroke (frequency 23.1% vs. 7.3% in the control group; P = 0.091) than the HLA-DRB1*04:10-negative group.