RPRD1B and colorectal carcinoma: To validate gene‐dosage effect of POFUT1, EIF6 and RPRD1B in colorectal tumors, we evaluated the relation between DNA copy numbers, RNA and protein expression of these genes in The Cancer Genome Atlas (TCGA) Provisional CRC data set.30, 31 Gene‐dosage effect was confirmed for each of these three genes in this data set on both RNA (n = 382) and protein level (n = 90), as gene and protein expression was higher when the DNA copy of the gene was gained or amplified (Figs. S8–S10).