CDKN2B-AS1 and periodontitis: The lncRNA antisense noncoding RNA in the INK4 locus (ANRIL), also known as cyclin-dependent kinase inhibitor 2B antisense RNA (CDKN2BAS), is located on the 9p21.3 locus and involved in the process of development and progression of many chronic diseases including CVD, intracranial aneurysm, and periodontitis (8,9).