The relevance of targeting the ELR+CXCL/CXCR1/2 axis was assessed by correlating the intra-tumor mRNA levels of ELR+CXCL cytokines to disease free/progression free (DFS/PFS) (Table 1A) and overall survival (OS) (Table 1B) of the RCC and HNSCC patients. The gene discussed is CXCR1; the disease is head and neck squamous cell carcinoma.