BIRC5 and neuroblastoma: Consistent with our results from neuroblastoma cells with amplification of 17q or ectopic expression of survivin, which leads to an increase in aerobic glycolysis, also the treatment with SMAC-mimetics increases the glucose consumption and lactate generation in SH-EP/Ctr cells, but not in SH-EP/shSurv cells (Figure 3C and 3D).