MYC and neuroblastoma: To further explore the specificity of the observed sensitization to 2DG by co-treatment with SMAC- mimetics, we analyzed the effect of LCL161 on two other neuroblastoma cell lines which do not carry an 17q amplification, but are derived from biopsies of patients with stage M (old classification stage 4 35) and further differ in the N-MYC status 36.