Thisamplification-related elevated expression has been shownto promote tumorigenesis in breast cancer cells throughconstitutive activation of the Akt signaling pathway(Sheet al., 2008)or chemotherapy resistance in solid tumorssuch as lung cancer (Engelman et al., 2007) and breastcancer(Li et al., 2010). This evidence concerns the gene AKT1 and lung carcinoma.