The phosphorylated (P)-ERK1/2:ERK1/2 and P-ERK5:ERK5 ratios were increased in the DLBCL cell line, while the P-JNK:JNK ratio was decreased, and no significant difference in the P-P38:P38 ratio was observed (Fig. 4a–c). The gene discussed is MAPK8; the disease is diffuse large B-cell lymphoma.