DDAH2 and type 2 diabetes mellitus: In an attempt to clarify this issue, we investigated the association of the rs9267551 polymorphism in the DDAH2 gene with MI in T2DM patients taking advantage of the observation that this polymorphism has a functional impact with the minor C allele exhibiting a higher transcriptional activity resulting in enhanced DDAH2 expression along with higher nitric oxide release in primary human endothelial cells [22].