TNFRSF18 and Alzheimer disease: To verify whether the expression of both GITR and FoxP3 in the hippocampus of 3xTg-AD mice was associated with lymphocytes infiltration, immunostaining for CD3 was performed in the CA2 and CA3 hippocampal areas of untreated 3xTg-AD mice revealing a substantial immunoreactivity in both areas as compared with wild type mice.