Various signaling pathways, such as the PI3K/Akt [25], STAT [56], intrinsic apoptosis [57, 58], Hedgehog [59] and Akt/mTOR signaling pathways [31, 60], are linked to the pathogenesis of different breast cancer subsets and considered as potential targets for breast cancer therapy. The gene discussed is MTOR; the disease is breast carcinoma.