After a 12 week trial and daily intake of 56 g almonds, compared with a no-nut control diet, plasma apoB, apoB/apoA-1 ratio, T-C, LDL-C, and LDL-C/HDL-C ratio decreased significantly by 15.6%, 17.4%, 6.0%, 11.6%, and 9.7%, respectively, in patients with T2DM [31]. This evidence concerns the gene APOB and type 2 diabetes mellitus.