Chemerin did not correlate with AFP (r = −0.20, p = 0.22), CEA (r = 0.08, p = 0.57) and CA19-9 (r = 0.15, p = 0.31) in the cancer patients of the whole cohort and when both groups were analyzed separately (CRC: AFP r = −0.08, p = 0.77, CEA r = 0.18, p = 0.34 and CA19-9 r = 0.31, p = 0.09; HCC: AFP r = −0.15 p = 0.48, CEA r = −0.19, p = 0.41 and CA19-9 r = −0.42, p = 0.07 ). Here, RARRES2 is linked to hepatocellular carcinoma.