Accordingly, serum chemerin did not change with extent of steatosis, inflammation or fibrosis in the whole study group (Figure 5A–C) and when both cohorts were analyzed separately (HCC: p = 0.71 for steatosis, p = 0.31 for inflammation and p = 0.75 for fibrosis; CRC: p = 0.77 for steatosis, p = 0.44 for inflammation and p = 0.05 for fibrosis It is important to note that in the group of tumor patients there was only one patient in the following subgroups: steatosis grade 3, inflammation grade 2 and fibrosis grade 2. This evidence concerns the gene RARRES2 and hepatocellular carcinoma.