EIF4EBP1 and Merkel cell skin cancer: The biological relevance of sT-mediated 4E-BP1 phosphorylation in MCPyV’s lifecyle or MCPyV-induced MCC is not completely understood, but sT-induced hyperphosphorylation of 4E-BP1 can lead to cap-dependent translation, which may contribute to MCPyV’s role in MCC because dysregulated cap-dependent translation promotes tumorigenesis [89].