Multivariate logistic regression analysis also identified significant risk association for the RET S904S SNP in the hereditary MTC group (OR = 2.82; 1.64‐4.86; P < .001) (Table 2) whereas for CDKN2A (OR = 1.89; 95% CI = 1.20‐2.98; P = .006) and NAT2 SNP (OR = 1.62; 95% CI = 1.17‐2.25; P = .004) in the sporadic MTC group (Table 2). This evidence concerns the gene CDKN2A and medullary thyroid gland carcinoma.