Reactivation of telomerase in human malignancies has also been linked to TERT amplification.44, 45 In fact, the TERT gene locus was found to be amplified in various cancers including lung, breast, cervical carcinomas, and FTC,28, 45, 46, 47 prompting us to examine the TERT gene for copy number alterations in different types of thyroid cancer. This evidence concerns the gene TERT and cancer.