EDN1 and chronic kidney disease: The relations of several serum AGEs and dicarbonyls with sVCAM-1 and sThrombomodulin agree with and extend results of previous studies in CKD [44], CKD5-ND [30] and CKD5-D [24,26], which observed associations of plasma pentosidine [24,30], serum CML [44] and SAF [26] with biomarkers of ED, for example, sVCAM-1 [30,44], endothelin-1 [24], post-occlusive peak reactive hyperemia [44], thermal hyperemia [44] and flow-mediated dilation [26].