RUNX3 and lung cancer: BRD2 is a member of the bromodomains and extra‐terminal domain (BET) family, which interacts with acetylated chromatin and transcription complexes to control transcription, and can bind MYC to drive tumorigenesis in lung cancer.23 BRD2 interacts with Runx3 to form a complex, and inactivation of Runx3 is an important early event in the development of LUAD.24