BCL11B and cancer: BCL11B encodes a Kruppel‐like zinc finger protein that was previously identified as an integration site of HPV16 in at least two ICCs43, 62 and is mutated in other human cancers, most notably T‐lymphocyte tumors.44, 45, 63, 64, 65 The occurrence of the two junctions at nearby genomic positions in BCL11B suggested that the 3980 bp HPV70 segment comprised a single insertion at this site (Figure 2A).