Among women with breast and ovarian cancer or TNBC ≤60, PVs in BRCA1/2 were more frequent than PVs in other breast and/or ovarian cancer genes, whereas PVs in other breast and/or ovarian cancer genes were more frequent than BRCA1/2 among women with breast and uterine/endometrial cancer or breast cancer <50 and additional breast cancer primary. Here, BRCA1 is linked to breast cancer.