FECH and urinary bladder carcinoma: However, overexpression of miR-210 significantly reduced FECH mRNA levels in rat neonatal cardiomyocytes, it did not induce a similar effect on human embryonic kidney cells (HEK-293).35 Whether the lowered expression of FECH seen in glioma, colon and bladder cancers is due to regulation by microRNAs, such as miR-210, needs further exploration.