In addition, the identification of KRAS CNG and mutation as a poor prognostic factor, could also help to identify patients with resectable disease with higher risk of early tumour relapse, who may benefit from additional staging imaging before surgery (i.e. Magnetic resonance imaging of the liver or 18 fluorodeoxyglucose (FDG)-positron emission tomograph) or potential neo-adjuvant. Here, KRAS is linked to neoplasm.