CDH1 and cancer: Following FACS isolation, imaging of GFP in cancer cells and matched CAFs confirmed that CAFs isolated from both GEMMs do not express E-cadherin-GFP (Fig. 1b), while immunohistochemistry (IHC) and immunofluorescence analyses of markers for CAFs29 (Fig. 1c) and pancreatic epithelial cancer cells (Fig. 1d) validated the identity and purity of the isolated CAFs.