Kaplan–Meier analysis using our IHC data indicated that HCC patients with high SOCS5 expression had significantly shorter median OS and disease-free survival (DFS) than those with low SOCS5 expression (OS: 36.5 vs. 55.8 months, respectively; DFS: 29.4 vs. 48.3 months, respectively; Fig. 1f, g). This evidence concerns the gene SOCS5 and hepatocellular carcinoma.