IL2 and skin squamous cell carcinoma: In this study, although IL-2 increased in CSCC cases, the Th1/Th2 ratio was lowest in CSCC cases, therefore the IL-2/IL-10 drift could better reflect the immune state of the body, and it indicates that the imbalance of T cell immune response was probably more and more obvious with the progression of the disease, causing Th1 to drift to Th2 in the body, and decrease cellular immune function.