It is important to note that the association between rs6993770 and rs10738760 with hypercholesterolemia and MetS, respectively, has previously explained a minor fraction of VEGF plasma levels (2% and 5%, respectively), implying that VEGF might be a player in hypercholesterolemia and MetS, yet other additional molecules are still to be identified. Here, VEGFA is linked to Hypercholesterolemia.