The analysis showed that total IgE mean levels were significantly higher in children with AD compared to those without AD at the age of 6 months (129.56 vs. 19.7 UI/mL, P < 0.001) and 13–24 months (314.05 vs. 118.39 UI/mL, P = 0.017). The gene discussed is IGHE; the disease is Alzheimer disease.