The vast majority presented with nephrotic syndrome (613/752, 81.5%), hypertension (466/752, 61.9%), hypoalbuminaemia, defined as serum albumin levels<3gr/dL, (481/752, 63.9%) and dyslipidaemia, defined as serum cholesterol >250mg/dl and/or serum triglycerides >160mg/dl, (482/752, 64%). The gene discussed is ALB; the disease is Hypertension.