By contrast, in contemporaneous experiments, cardiomyocytes expressing CaV-aβlator via adenovirus-mediated infection displayed virtually no CaV1.2 currents, demonstrating an exceptional CaV-aβlation efficiency in this system (Figure 5a,b; Ipeak,0mV = −1.0 ± 0.3 pA/pF, n = 9). This evidence concerns the gene CACNA1C and infection.