As shown in Table 2, for PRDX1 (HR = 1.52, 95% CI: 1.06–2.17, P = 0.022), PRDX4 (HR = 1.58, 95% CI: 1.10–2.27, P = 0.012), and PRDX6 (HR = 1.49, 95% CI: 1.04–2.13, P = 0.027), high mRNA expression was associated with unfavorable OS in luminal A BrCa patients, respectively. The gene discussed is PRDX4; the disease is invasive breast carcinoma.