To examine whether CDEs can be absorbed by CRC cells, we labeled CDEs with PKH-67 green dye and incubated these PKH67-labeled CDEs (PKH-67 are lipophilic cell tracking dyes with long aliphatic tails into lipid regions of exactly lipophilic on exosomes CDEs) with SW480 cells for 12 h. The gene discussed is PDXK; the disease is colorectal carcinoma.