T cells lacking CD73 show accelerated production of pro-inflammatory and profibrotic cytokines (IL-2, IFN-γ, and IL-17) (Borg et al., 2017) presumably accounting for down-modulated CD73 expression on Th and Tcyt subsets in MAS vs. SAS patients vs. HVs. This evidence concerns the gene IL17A and SATB2 associated disorder.