Several studies further supported that thyroid autoimmunity increased the risk of complications of pregnancy loss, recurrent miscarriage, and preterm delivery.6, 15, 36 It was reported that the thyroid antibodies were found in 5%‐15% of women at reproductive age without thyroid dysfunctions.6 We observed moderately increased aTPO IgG in all three groups including healthy controls but found no significant difference between those groups. This evidence concerns the gene ATP5PO and thyroid gland disorder.