By contrast, however, in the ROC analyses for differentiating patients with sporadic miscarriage and RPL (Figure 2B), the corresponding AUCs for the aPT IgM, aPE IgG, aPE IgM, aEM IgG and combined aPE IgG and aEM IgG were 0.552, 0.508, 0.636, 0.600, and 0.575, respectively, indicating much lower efficiency in discriminating the above two groups. This evidence concerns the gene CD40LG and spontaneous abortion.