CRP and bacterial infectious disease with sepsis: In the diagnosis of respiratory tract infections and monitoring of bacterial sepsis, inflammatory markers, such as C reactive protein (CRP) and procalcitonin (PCT) in blood, have proven useful to guide antibiotic therapy and reduce antibiotic use.18–21 Currently, point-of-care (POC) CRP measurements are recommended by Dutch guidelines for the general practitioners to guide antibiotic treatment for acute respiratory tract infections.