Next to these kind of wearables, the developed measurement instrument also could be applied to user-centered disease monitoring wearable devices such as wearable cameras that enhance chronic disease self-management [87], insulin monitors and pumps in the treatment of diabetes [19], smart gloves that assist rheumatoid arthritis patients in applying therapy [88], and medical-grade electrocardiogram wristwatches that assist cardiac patients to detect heart arrhythmia [89]. Here, INS is linked to cardiac arrhythmia.