Our study has demonstrated that 77.4% of the kindred (24/31, 24 families including 24 definite HHT cases, 9 possible HHT cases, 4 carriers) had ACVRL1 or ENG variant, which is in accordance with the findings of previous reports (Bayrak‐Toydemir et al., 2006; Chen et al., 2013; Heimdal et al., 2016). The gene discussed is ENG; the disease is hereditary hemorrhagic telangiectasia.