PON1 and vascular dementia: As forPON1 and DNA methylation, Fiorito et al found a general inverse relationship between B‐vitamins intake and DNA methylation of PON1. 29 The methylation of PON1 was also linked to vascular dementia which confirmed by Bednarska‐Makaruk et al.30 Interestingly, the experimental group suffered from the disease also had lower intake of vitamin B than the normal group.