Overall, there was supportive evidence from the CHi-C data for chromatin interactions between the LD-defined CLL risk loci with promoters of 15 of the 37 candidate genes (41%) identified in the eQTL analysis, including TLE3 as a target of the rs11637565 LD region as well as UBR5 as a target of the rs2511713LD region (Fig. 4). Here, TLE3 is linked to B-cell chronic lymphocytic leukemia.